EXPH5 Antibody, HRP conjugated

Datasheet

Code	CSB-PA843342LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EXPH5 Polyclonal antibody

Uniprot No.

Q8NEV8

Target Names

EXPH5

Alternative Names

EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Exophilin-5 protein (1235-1490AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

May act as Rab effector protein and play a role in vesicle trafficking.

Gene References into Functions

Mutations in EXPH5 protein, human have been implicated in the physiopathology of Epidermolysis bullosa simplex. PMID: 27384765
The results identify a further EXPH5 pedigree suggest that mutations in EXPH5 should be considered as a possible candidate gene for recessive or sporadic cases of mild generalized EBS. PMID: 26211931
Here, we report the second family with two EXPH5 mutations in epidermolysis bullosa simplex. PMID: 24005056
our findings identify an unexpected role for Slac2-b in inherited skin fragility and expand the clinical spectrum of human disorders of GTPase effector proteins. PMID: 23176819
Slac2-b/KIAA0624 contains an N-terminal Slp homology domain (SHD) (PMID: 11327731). The SHD of Slac2-b specifically and directly binds the GTP-bound form of Rab27A (J. Biol. Chem. 277, (2002) 9212-9218; PMID: 11773082). PMID: 11773082

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Involvement in disease

Epidermolysis bullosa, non-specific, autosomal recessive (EBNS)

Tissue Specificity

Expressed in keratinocytes.

Database Links

HGNC: 30578

OMIM: 612878

KEGG: hsa:23086

STRING: 9606.ENSP00000265843

UniGene: Hs.28540

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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